Product Name :
ISPA-28
Description:
ISPA-28 is a specific plasmodial surface anion channel (PSAC) antagonist. ISPA-28 binds directly and reversibly to CLAG3.
CAS:
1006335-39-2
Molecular Weight:
408.45
Formula:
C21H24N6O3
Chemical Name:
N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro-1,2-oxazole-5-carboxamide
Smiles :
CN1C(C)=C(NC(=O)C2CC(=NO2)C2=CN(CC)N=C2C)C(=O)N1C1C=CC=CC=1
InChiKey:
YMLINDVVJXDIRW-UHFFFAOYSA-N
InChi :
InChI=1S/C21H24N6O3/c1-5-26-12-16(13(2)23-26)17-11-18(30-24-17)20(28)22-19-14(3)25(4)27(21(19)29)15-9-7-6-8-10-15/h6-10,12,18H,5,11H2,1-4H3,(H,22,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Vudalimab} medchemexpress|{Vudalimab} CTLA-4|{Vudalimab} Protocol|{Vudalimab} Data Sheet|{Vudalimab} supplier|{Vudalimab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Cryptotanshinone} MedChemExpress|{Cryptotanshinone} Autophagy|{Cryptotanshinone} Biological Activity|{Cryptotanshinone} In stock|{Cryptotanshinone} supplier|{Cryptotanshinone} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24013184
Additional information:
ISPA-28 is a specific plasmodial surface anion channel (PSAC) antagonist. ISPA-28 binds directly and reversibly to CLAG3.|Product information|CAS Number: 1006335-39-2|Molecular Weight: 408.45|Formula: C21H24N6O3|Chemical Name: N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro-1,2-oxazole-5-carboxamide|Smiles: CN1C(C)=C(NC(=O)C2CC(=NO2)C2=CN(CC)N=C2C)C(=O)N1C1C=CC=CC=1|InChiKey: YMLINDVVJXDIRW-UHFFFAOYSA-N|InChi: InChI=1S/C21H24N6O3/c1-5-26-12-16(13(2)23-26)17-11-18(30-24-17)20(28)22-19-14(3)25(4)27(21(19)29)15-9-7-6-8-10-15/h6-10,12,18H,5,11H2,1-4H3,(H,22,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ISPA-28 is only effective as an inhibitor of Dd2 channels (K0.5 values of 56 nM and 43 μM for Dd2 and HB3 channels, respectively).|Products are for research use only. Not for human use.|
