Product Name :
HIF-1 inhibitor-1
Description:
HIF-1 inhibitor-1 is an aryl carboxamide compound and a potent hypoxia-inducible factor 1 (HIF-1) inhibitor with an IC50 of 0.32 μM for the cancer metastasi. . Liu M, et al. Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis. J Med Chem. 2019 Oct 24;62(20):9299-9314.
CAS:
2380261-53-8
Molecular Weight:
350.39
Formula:
C21H19FN2O2
Chemical Name:
N-[2-(2-fluorophenyl)ethyl]-5-(2-methoxyphenyl)pyridine-2-carboxamide
Smiles :
COC1=CC=CC=C1C1=CN=C(C=C1)C(=O)NCCC1=CC=CC=C1F
InChiKey:
JZEJSNMITKBPGZ-UHFFFAOYSA-N
InChi :
InChI=1S/C21H19FN2O2/c1-26-20-9-5-3-7-17(20)16-10-11-19(24-14-16)21(25)23-13-12-15-6-2-4-8-18(15)22/h2-11,14H,12-13H2,1H3,(H,23,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{R-Phycoerythrin} web|{R-Phycoerythrin} {Fluorescent Dye}|{R-Phycoerythrin} Purity & Documentation|{R-Phycoerythrin} In stock|{R-Phycoerythrin} supplier|{R-Phycoerythrin} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
HIF-1 inhibitor-1 is an aryl carboxamide compound and a potent hypoxia-inducible factor 1 (HIF-1) inhibitor with an IC50 of 0.{{Peroxidase, Horseradish} web|{Peroxidase, Horseradish} Metabolic Enzyme/Protease|{Peroxidase, Horseradish} Immunology/Inflammation|{Peroxidase, Horseradish} Purity & Documentation|{Peroxidase, Horseradish} Data Sheet|{Peroxidase, Horseradish} supplier} 32 μM for the cancer metastasi. . Liu M, et al. Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis. J Med Chem. 2019 Oct 24;62(20):9299-9314.|Product information|CAS Number: 2380261-53-8|Molecular Weight: 350.39|Formula: C21H19FN2O2|Chemical Name: N-[2-(2-fluorophenyl)ethyl]-5-(2-methoxyphenyl)pyridine-2-carboxamide|Smiles: COC1=CC=CC=C1C1=CN=C(C=C1)C(=O)NCCC1=CC=CC=C1F|InChiKey: JZEJSNMITKBPGZ-UHFFFAOYSA-N|InChi: InChI=1S/C21H19FN2O2/c1-26-20-9-5-3-7-17(20)16-10-11-19(24-14-16)21(25)23-13-12-15-6-2-4-8-18(15)22/h2-11,14H,12-13H2,1H3,(H,23,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24423657 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
