Product Name :
Biotin-PEG4-methyltetrazine
Description:
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1835759-81-3
Molecular Weight:
589.71
Formula:
C27H39N7O6S
Chemical Name:
5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-{2-[2-(2-{2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy}ethoxy)ethoxy]ethyl}pentanamide
Smiles :
CC1N=NC(=NN=1)C1C=CC(=CC=1)OCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21
InChiKey:
FTGDGKKLLGMCLG-LSQMVHIFSA-N
InChi :
InChI=1S/C27H39N7O6S/c1-19-31-33-26(34-32-19)20-6-8-21(9-7-20)40-17-16-39-15-14-38-13-12-37-11-10-28-24(35)5-3-2-4-23-25-22(18-41-23)29-27(36)30-25/h6-9,22-23,25H,2-5,10-18H2,1H3,(H,28,35)(H2,29,30,36)/t22-,23-,25-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Biotin-PEG4-methyltetrazine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1835759-81-3|Molecular Weight: 589.71|Formula: C27H39N7O6S|Chemical Name: 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-{2-[2-(2-{2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy}ethoxy)ethoxy]ethyl}pentanamide|Smiles: CC1N=NC(=NN=1)C1C=CC(=CC=1)OCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21|InChiKey: FTGDGKKLLGMCLG-LSQMVHIFSA-N|InChi: InChI=1S/C27H39N7O6S/c1-19-31-33-26(34-32-19)20-6-8-21(9-7-20)40-17-16-39-15-14-38-13-12-37-11-10-28-24(35)5-3-2-4-23-25-22(18-41-23)29-27(36)30-25/h6-9,22-23,25H,2-5,10-18H2,1H3,(H,28,35)(H2,29,30,36)/t22-,23-,25-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (84.{{Danavorexton} MedChemExpress|{Danavorexton} GPCR/G Protein|{Danavorexton} NF-κB|{Danavorexton} Purity & Documentation|{Danavorexton} In stock|{Danavorexton} supplier} 79 mM; Need ultrasonic).{{Tebuconazole} site|{Tebuconazole} Fungal|{Tebuconazole} Protocol|{Tebuconazole} References|{Tebuconazole} supplier|{Tebuconazole} Autophagy} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23577779 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
