Product Name :
ENMD-2076 L-(+)-Tartaric acid
CAS No.:
1291074-87-7
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CN1CCN(CC1)C2=NC(=NC(=C2)NC3=N[NH]C(=C3)C)\C=C\C4=CC=CC=C4.OC(C(O)C(O)=O)C(O)=O
Product Description :
ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase 2.
Formula:
C25H31N7O6
Molecular Weight :
525.56
Synonyms:
Additional Information:
|CAS No.{{1834513-65-3} site|{1834513-65-3} Purity & Documentation|{1834513-65-3} In Vitro|{1834513-65-3} manufacturer} 1291074-87-7 ; |Formula C25H31N7O6 ; |Molecular Weight 525.56 ; |SMILES CN1CCN(CC1)C2=NC(=NC(=C2)NC3=N[NH]C(=C3)C)\C=C\C4=CC=CC=C4.OC(C(O)C(O)=O)C(O)=O ; |Target VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα ; |Product Description ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.{{1086136-22-2} web|{1086136-22-2} Technical Information|{1086136-22-2} In stock|{1086136-22-2} supplier} 86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα.PMID:29023086 Phase 2. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO
