Product Name :
Cbl-b-IN-1
Description:
Cbl-b-IN-1 (example 519) is a Cbl-b inhibitor, extracted from patent WO2019148005A1, with an IC50 <100 nM.
CAS:
2368841-84-1
Molecular Weight:
498.62
Formula:
C29H34N6O2
Chemical Name:
4-({5-azaspiro[2.4]heptan-5-yl}methyl)-6-cyclopropyl-N-(3-{3-[(4-methyl-4H-1,2,4-triazol-3-yl)methyl]oxetan-3-yl}phenyl)pyridine-2-carboxamide
Smiles :
CN1C=NN=C1CC1(COC1)C1C=C(C=CC=1)NC(=O)C1=CC(CN2CCC3(C2)CC3)=CC(=N1)C1CC1
InChiKey:
VXMQSDNIOKDJHW-UHFFFAOYSA-N
InChi :
InChI=1S/C29H34N6O2/c1-34-19-30-33-26(34)14-29(17-37-18-29)22-3-2-4-23(13-22)31-27(36)25-12-20(11-24(32-25)21-5-6-21)15-35-10-9-28(16-35)7-8-28/h2-4,11-13,19,21H,5-10,14-18H2,1H3,(H,31,36)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Cbl-b-IN-1 (example 519) is a Cbl-b inhibitor, extracted from patent WO2019148005A1, with an IC50 Product information|CAS Number: 2368841-84-1|Molecular Weight: 498.{{Patritumab deruxtecan} MedChemExpress|{Patritumab deruxtecan} Antibody-drug Conjugate/ADC Related|{Patritumab deruxtecan} Protocol|{Patritumab deruxtecan} Formula|{Patritumab deruxtecan} custom synthesis|{Patritumab deruxtecan} Autophagy} 62|Formula: C29H34N6O2|Chemical Name: 4-({5-azaspiro[2.{{Isoliquiritigenin} site|{Isoliquiritigenin} Anti-infection|{Isoliquiritigenin} Biological Activity|{Isoliquiritigenin} In Vivo|{Isoliquiritigenin} custom synthesis|{Isoliquiritigenin} Epigenetic Reader Domain} 4]heptan-5-yl}methyl)-6-cyclopropyl-N-(3-{3-[(4-methyl-4H-1,2,4-triazol-3-yl)methyl]oxetan-3-yl}phenyl)pyridine-2-carboxamide|Smiles: CN1C=NN=C1CC1(COC1)C1C=C(C=CC=1)NC(=O)C1=CC(CN2CCC3(C2)CC3)=CC(=N1)C1CC1|InChiKey: VXMQSDNIOKDJHW-UHFFFAOYSA-N|InChi: InChI=1S/C29H34N6O2/c1-34-19-30-33-26(34)14-29(17-37-18-29)22-3-2-4-23(13-22)31-27(36)25-12-20(11-24(32-25)21-5-6-21)15-35-10-9-28(16-35)7-8-28/h2-4,11-13,19,21H,5-10,14-18H2,1H3,(H,31,36)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 60 mg/mL (120.PMID:32644399 33 mM; ultrasonic and warming and heat to 60°C).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
