Product Name :
Neomycin . sulfate
Sequence:
Purity:
≥90% (TLC)
Molecular Weight:
614.7 . 294.2
Solubility :
Soluble in water (10mg/ml).
Appearance:
White to off-white solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended.
Description:
Inhibitor of PLC and PLD Aminoglycoside antibiotic that inhibits translation by binding to the small subunit of prokaryotic ribosomes.{{2417489-10-0} medchemexpress|{2417489-10-0} Protocol|{2417489-10-0} In Vivo|{2417489-10-0} supplier} Inhibitor of phospholipase C (PLC; IC50=1-10µM) due to binding to inositol phospholipids. Neomycin inhibits phosphatidylcholine-phospholipase D activity (IC50=65µM). Blocks voltage sensitive Ca2+ channels without affecting Na+/Ca2+ antiporters in nerve cells. Induces PLA2 activation in human platelets.{{1818885-28-7} MedChemExpress|{1818885-28-7} Technical Information|{1818885-28-7} Data Sheet|{1818885-28-7} manufacturer}
CAS :
1405-10-3
Solubility:
Soluble in water (10mg/ml).PMID:20301329
Formula:
C23H46N6O13 . 3H2SO4
Additional Information :
| Appearance White to off-white solid. | CAS 1405-10-3 | Couple Target Calcium channel, PLC, PLD | Couple Type Blocker, Inhibitor | Formula C23H46N6O13 . 3H2SO4 | MI 14: 6454 | MW 614.7 . 294.2 | Purity ≥90% (TLC) | RTECS QP4375000 | Solubility Soluble in water (10mg/ml). | Unit of Measure (UM) g
