Product Name :
LTV-1
Description:
LTV-1 is a potent lymphoid tyrosine phosphatase (LYP) inhibitor in T cells with an IC50 of 508 nM. LTV-1 has the potential for autoimmunity treatment.
CAS:
347379-29-7
Molecular Weight:
472.51
Formula:
C26H20N2O5S
Chemical Name:
3-[(4-[(5E)-1-(2-methylphenyl)-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-ylidene]methylphenoxy)methyl]benzoic acid
Smiles :
CC1=CC=CC=C1N1C(=S)NC(=O)/C(=C\C2C=CC(=CC=2)OCC2=CC(=CC=C2)C(O)=O)/C1=O
InChiKey:
DSYDHTCEVHUCPE-KGENOOAVSA-N
InChi :
InChI=1S/C26H20N2O5S/c1-16-5-2-3-8-22(16)28-24(30)21(23(29)27-26(28)34)14-17-9-11-20(12-10-17)33-15-18-6-4-7-19(13-18)25(31)32/h2-14H,15H2,1H3,(H,31,32)(H,27,29,34)/b21-14+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
LTV-1 is a potent lymphoid tyrosine phosphatase (LYP) inhibitor in T cells with an IC50 of 508 nM. LTV-1 has the potential for autoimmunity treatment.PSMA-11 Protocol |Product information|CAS Number: 347379-29-7|Molecular Weight: 472.Linezolid Biological Activity 51|Formula: C26H20N2O5S|Chemical Name: 3-[(4-[(5E)-1-(2-methylphenyl)-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-ylidene]methylphenoxy)methyl]benzoic acid|Smiles: CC1=CC=CC=C1N1C(=S)NC(=O)/C(=C\C2C=CC(=CC=2)OCC2=CC(=CC=C2)C(O)=O)/C1=O|InChiKey: DSYDHTCEVHUCPE-KGENOOAVSA-N|InChi: InChI=1S/C26H20N2O5S/c1-16-5-2-3-8-22(16)28-24(30)21(23(29)27-26(28)34)14-17-9-11-20(12-10-17)33-15-18-6-4-7-19(13-18)25(31)32/h2-14H,15H2,1H3,(H,31,32)(H,27,29,34)/b21-14+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 22.PMID:33085338 73 mg/mL (48.10 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|LTV-1 (1.25-40 μM) has no notable effect on cell viability (metabolic rate assay), even at the highest concentration tested (40 μM). Thus, LTV-1 is not cytotoxic in HeLa cells, Jurkat TAg T cells and peripheral blood mononuclear cells (PBMC).|Products are for research use only. Not for human use.|
