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TRAIL-R2 (human) monoclonal antibody (DJR2-4)
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DR5 is 55kDa member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262.779353-01-4 supplier It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.745013-59-6 medchemexpress
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| Alternative Name TRAIL receptor 2, DR5, Death receptor 5, KILLER, CD262, Trick2, Ly98, TNFRSF10B, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B | Application Flow Cytometry | Clone DJR2-4 | Formulation Liquid.PMID:30570996 In PBS, pH 7.2, containing 0.09% sodium azide. | Gene/Protein Identifier 8795 (Entrez GeneID) | Host Mouse | Immunogen Recombinant human TRAIL-R2 extracellular domain IgG1 Fc fusion protein. | Isotype IgG1 | Species Reactivity Human | UniProt ID O14763 | Unit of Measure (UM) µg
