Product Name :
TCO-PEG2-amine
Description:
TCO-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
CAS:
2141981-87-3
Molecular Weight:
300.39
Formula:
C15H28N2O4
Chemical Name:
(4Z)-cyclooct-4-en-1-yl N-2-[2-(2-aminoethoxy)ethoxy]ethylcarbamate
Smiles :
NCCOCCOCCNC(=O)OC1CCC=CCCC1 |c:16|
InChiKey:
XCPPYCGUCZZMQS-UPHRSURJSA-N
InChi :
InChI=1S/C15H28N2O4/c16-8-10-19-12-13-20-11-9-17-15(18)21-14-6-4-2-1-3-5-7-14/h1-2,14H,3-13,16H2,(H,17,18)/b2-1-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
TCO-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.|Product information|CAS Number: 2141981-87-3|Molecular Weight: 300.Valganciclovir manufacturer 39|Formula: C15H28N2O4|Chemical Name: (4Z)-cyclooct-4-en-1-yl N-2-[2-(2-aminoethoxy)ethoxy]ethylcarbamate|Smiles: NCCOCCOCCNC(=O)OC1CCC=CCCC1 |c:16||InChiKey: XCPPYCGUCZZMQS-UPHRSURJSA-N|InChi: InChI=1S/C15H28N2O4/c16-8-10-19-12-13-20-11-9-17-15(18)21-14-6-4-2-1-3-5-7-14/h1-2,14H,3-13,16H2,(H,17,18)/b2-1-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Varenicline manufacturer |Shelf Life: ≥12 months if stored properly.PMID:33115798 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:|Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.Products are for research use only. Not for human use.|
